The double-strand break-free approach increased functional GATA2 alleles and improved the engraftment of edited blood stem cells in mice ...

Targeted lipid nanoparticles generate CAR NK cells in mice, showing activity against cancer and autoimmune liver disease ...

John Wichelt discusses Kindeva’s Bridgeton facility, supporting injectable programs from clinical development through ...

Piers Ingram discusses the resurgence of immunology, engineering-led drug discovery, and why faster clinical execution will shape the next generation of medicines ...

Thoughtful label design and digital tools can help participants with dyslexia find and access essential clinical trial ...

An RNA sequencing and machine learning screening platform identified an RNA-processing factor that reduced markers of ...

First-in-human study demonstrates the potential of rapidly manufactured trispecific CAR T cells to deliver durable remissions ...

Pharma Integrates is a premier forum uniting senior leaders across pharma, life sciences, and healthcare to confront the challenges reshaping the industry — from commercial model transformation and ...

The narrative that small molecules are being displaced is, I think, significantly overstated. The excitement around cell therapies, antibody-drug conjugates, and ribonucleic acid-based approaches is ...

Adicet Bio has reported positive Phase I safety and efficacy data for prulacabtagene leucel (prula-cel), its investigational allogeneic gamma delta CAR T therapy, in patients with systemic lupus ...

Advanced Therapies Integrates unites industry leaders to address the next stage of the ATMP journey – translating scientific promise into therapies that reach patients at scale. As the field continues ...

Pregnancies after CAR T-cell therapy for autoimmune disease were reported without disease reactivation, according to early data from 14 pregnancies in 13 patients. The findings add to limited evidence ...