Every cell in the human body faces a chronic challenge: protecting its DNA. Whenever cells divide, their genetic material must be copied accurately. But DNA is continuously under attack, and when ...

The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP ...

The study, published in Proceedings of the National Academy of Sciences of the United States of America, deepens ...

A team of scientists in Norway has found evidence for a new mechanism for the development of cancer in children: They seem to ...

Thymine suffers more UV damage than uracil in lab tests, but its damage pathways could help explain its place in DNA.

Kiszala, the CEO and co-founder of intoDNA, to explore how a breakthrough in understanding DNA damage and repair could ...

Jonathan the giant tortoise has survived nearly two centuries on a remote Atlantic island, outliving empires and 31 governors ...

Some people with rectal cancer may now be able to skip chemotherapy, radiation and surgery. The U.S. Food and Drug ...

The world’s oldest land animal carries 287 unique gene variants involved in DNA repair and other defenses against aging, ...

Certainly also drugs that interact with DNA damage and repair. PARP inhibitors have a very fixed now role in how we take care ...

A large-scale reanalysis of 23,435 prokaryotic reference genomes confirms that complete NucS and canonical MutS-MutL mismatch ...

The world's oldest-known terrestrial animal — an Aldabra giant tortoise named Jonathan, estimated to be about 194 years old — ...