A new meta-analysis of 4,070 patients identifies EGFR L858R, poor performance status, and brain metastases as high-certency ...

C EGFR T790M gene variant face roughly 25 times the lung cancer risk of noncarriers, according to the largest-yet study of the variant. People with ance ...

Depending on dose, firmonertinib shrank tumors in 43% to 68% of patients as a first treatment for EGFR PACC-mutant lung ...

A form of lung cancer, which is found in about 10%–15% of Western patients and 40%–50% of Asian patients, is driven by a ...

For patients with EGFR-mutant lung adenocarcinoma whose cancer has already spread to the brain, third-generation EGFR-TKI ...

Significant advances have taken place in the management of patients with advanced and metastatic non–small-cell lung cancer (NSCLC) over the last 5 years. Traditionally, all advanced NSCLC patients ...

Cobas EGFR Mutation Test v2 sits on a steel lab bench, next to a rack of faintly pink plasma samples and a humming cobas 4800 analyzer. A lab tech in Chicago told me she likes watching the small ...

When Jeanne Szurek, 69, was diagnosed with stage IV epidermal growth factor receptor (EGFR)-positive lung cancer in 2024, she wondered if her two adult children were at a higher risk of developing the ...

The National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology, American Society of Clinical Oncology (ASCO) and European Society for Medical Oncology (ESMO) guidelines all ...

"Clinicians performing tumor biopsy need to ensure that there’s adequate tissue for both diagnosis and NGS testing. Having immediate pathology review of biopsy specimens in the operating room can ...