Human-induced pluripotent stem (iPS) cells are generated from somatic cells by introducing specific transcription factors. iPS cells are virtually indistinguishable from human embryonic stem (ES) ...
Retroviruses including lentiviruses possess purposeful machinery to insert their genes into host cell chromosomes. Delivering genes of choice in retroviral particles allows their stable and possibly ...
Lentiviral vectors are versatile gene delivery tools, capable of transducing a wide range of cell types. However, producing large volumes of high-quality lentiviruses can present several challenges.
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