How would you summarize your study for a lay audience? Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma ...

Immune cell trapping during allergic responses Mast cells, residing in tissues and critical for initiating inflammation, are filled with granules containing pro-inflammatory substances. These granules ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of Pittsburgh study published today in Science Translational Medicine. The ...

The function of mast cells, which are part of the immune system, is still a mystery. Scientists at the German Cancer Research Center (DKFZ) have now shown in mice: mast cells function as a sensor that ...

Q: My doctor thinks my mast cells are activating inappropriately and may be causing many of the symptoms I periodically have. Please tell me more about this condition. A: Mast cells are an important ...

Mast cell-expressed membrane protein 1 (MCEMP1) is a type II transmembrane protein predominantly expressed in myeloid lineage immune cells, including lung-resident mast cells and alveolar macrophages.

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...