A team of scientists in Norway has found evidence for a new mechanism for the development of cancer in children: They seem to ...

Certainly also drugs that interact with DNA damage and repair. PARP inhibitors have a very fixed now role in how we take care ...

The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP ...

Onderzoekers vonden DNA-herstelantilichamen bij kinderen jaren vóór de diagnose, wat hoop biedt op eerdere opsporing van ...

The world’s oldest land animal carries 287 unique gene variants involved in DNA repair and other defenses against aging, ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. The publication of two papers ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

A team of scientists in Norway has found evidence for a new, previously unknown mechanism for the development of cancer in ...

A large-scale reanalysis of 23,435 prokaryotic reference genomes confirms that complete NucS and canonical MutS-MutL mismatch ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During ...