Amide bonds are common in drugs because they are chemically stable, form readily and are biocompatible. They also help ...
The amide bond can be activated for cleavage under mild, neutral conditions by chemical derivatization, a British group has demonstrated (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201107117). Amide ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a biotech that synthesizes challenging peptides, announced today that it has begun commercializing its novel peptide manufacturing platform. The ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a leading biotech company specializing in the synthesis of complex peptides, announced today the appointment of Dr. Brad Pentelute as its new CEO ...
With its simple bicyclic skeleton, 2-quinuclidone doesn't look like it would be much of a challenge to make. But thanks to an unusually labile amide linkage, this modest lactam has eluded synthetic ...
Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide ...
In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity or alkalinity. Certain medicines make use of reactions ...
Novel, atom-efficient routes to amides from esters and carboxylic acids for more sustainable manufacturing. It is well known that amide-formation chemistry can be inefficient and warrants further ...
Spun out of MIT, Amide partners with biopharmas to accelerate peptide drug development – shortening synthesis to days instead of months – with peptides 3x longer than existing methods CAMBRIDGE, Mass.